Most books dealing with pharmacology in intensive care focus on the drugs used to treat the illness or injury. This book addresses the other most important issue for those caring for the critically ill - how organ function will affect the drugs used, and how to adapt management accordingly. Contents include: general principles of pharmacology; absorption, transport, and elimination of drugs; modes of action drugs; renal failure; hepatic failure; cardiac failure; gut failure; brain failure; lung failure; and children safe prescribing habits. By discussing organ failure in all major body parts separately, as well as having authoritative chapters on the principles of drug interactions, Pharmacology of the Critically Ill provides a uniquely reference in this vitally important aspect of intensive care. Contributors from leading specialists around the world ensure that this book has international relevance.