Nitric oxide research has emerged as one of the most important and new areas in bone and joint diseases. This book is the first one to draw together current knowledge on the actions of this mediator and its role in such common diseases as arthritis and osteoporosis. It introduces the basic biology and biochemistry of nitric oxide, the immune response and bone biology. It reviews in depth the facts we know today and the future promise of this exciting area of research. The book will give scientists and clinicians a unique insight into this increasingly important area. It also emphasises potential new treatments which exploit our understanding of the role of nitric oxide in bone and joint disease.