Microtubules

During the past decade, significant advances have been made in microtubule research. Molecular techniques have provided new insights into the tubulin dimer and its associated proteins, and video microscopy of microtubule assembly has led to revision of concepts of microtubule dynamics and intracellular transport of organelles. This major research work presents the recent microtubule literature in focused reviews organized around three central topics: the biochemistry and assembly of the tublin dimer; associated proteins and regulation of microtubule function; and microtubule organization and function in the cell.