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Provides a comprehensive review of nicotinic receptors–from the molecular level to clinical applications. Covers the emerging molecular biological advances in the cloning of nAChRs; the localization and regulation of these receptors; the role these receptors have in central nervous disorder (CNS) functions; the in vivo pharmacology; and the therapeutic opportunities that exist for agents that selectively interact with these receptors to treat CNS disorders.
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Provides a comprehensive review of nicotinic receptors–from the molecular level to clinical applications. Covers the emerging molecular biological advances in the cloning of nAChRs; the localization and regulation of these receptors; the role these receptors have in central nervous disorder (CNS) functions; the in vivo pharmacology; and the therapeutic opportunities that exist for agents that selectively interact with these receptors to treat CNS disorders.