Chemistry: Structure and Dynamics, 5th Edition emphasizes deep understanding rather than comprehensive coverage along with a focus on the development of inquiry and reasoning skills. While most mainstream General Chemistry texts offer a breadth of content coverage, the Spencer author team, in contrast, focuses on depth and reader preparation for future studies. The fifth edition is revised in keeping with our commitment to the chemical education community and specifically the POGIL (Process Oriented Guided Inquiry Learning) Project. This text reflects two core principles, first that the concepts that are covered are fundamental building blocks for understanding chemistry and second, that the concepts should be perceived by the readers as being directly applicable to their interests and careers. The authors further provide this core coverage using 1 of 3 models; data-driven, chemical theories and reader understanding, which allows for a more concrete foundation on which readers build conceptual understanding.