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This book provides an overview of different protein kinases - structure, function, regulation, and their role in cancer. It combines kinase biology with chemistry and pharmacology applications for discovery and development of cancer drugs. The text also describes existing and emerging kinase inhibitors, focusing mostly on small molecules but also alternative approaches like therapeutic antibodies. It provides an important resource that helps pharmaceutical researchers understand and work in this dynamic area of cancer drug research.
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This book provides an overview of different protein kinases - structure, function, regulation, and their role in cancer. It combines kinase biology with chemistry and pharmacology applications for discovery and development of cancer drugs. The text also describes existing and emerging kinase inhibitors, focusing mostly on small molecules but also alternative approaches like therapeutic antibodies. It provides an important resource that helps pharmaceutical researchers understand and work in this dynamic area of cancer drug research.