Studies of vaccines derived from carbohydrate antigens have seen great progress. Synthetic carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids, have been explored or used to prevent and treat bacterial and viral infections, cancer, and other diseases. This book discusses these developments with a focus on glycoimmunology including the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines. It approaches vaccine design from a chemistry and molecular focus, different from past work but in-tune with current advances, providing a single, convenient source of state-of-the-art information from leading authorities in the field.