A Manual of Adverse Drug Interactions

Adverse drug reactions, many of them ascribable to interactions with other drugs or with chemical substances in food or the environment, are thought to cause or complicate one in 20 of hospital admissions. The text is divided into two parts: Part 1 comments on drug interactions and their mechanisms, on a pharmacokinetic and pharmacodynamic level, while Part 2 consists of drug interaction tables, divided and subdivided into categories of disorders, and the drugs used in the treatment of these disorders. If safety in drugs is to improve, education of prescribers is vitally important. The real threat, as the authors remind us, is the ignorance of practitioners, not the drug itself. The volume therefore seeks to prevent a potential backlash when drugs are used in combination with other drugs or chemical substances.