Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease

7 9/16 X 10 5/16 in I. VASOPRESSIN AND OXYTOCIN IN EVOLUTION, SEXUAL DICHOTOMY AND STRESS Nonapeptides and the evolutionary patterning of sociality. Sex differences in vasopressin and oxytocin innervation of th e brain. The parvocellular vasopressinergic system and resp onsiveness of the hypothalamic pituitary adrenal axis during chronic str ess.

II. GENETICS MEETS BEHAVIOR Experimental approaches for the study of oxytocin and vasopressin gene expression in the central nervous system. Oxytocin knockout mice: a model for studying stress-related and ingestive behaviors. The role of the vasopressin 1b receptor in aggression and other social behaviors. Behavioral studies using temporal and s patial inactivation of the oxytocin receptor. New aspects o f oxytocin receptor function revealed by knockout mice: sociosexual beha viour and control of energy balance.

III. RE GULATION OF VASOPRESSIN AND OXYTOCIN RELEASE Regulation of vasopressin release by co-released neurotransmitters: Mechanisms of puri