Frontiers in High Pressure Biochemistry and Biophysics

Preface. I. Introduction. High pressure effects on biol ogical macromolecules: From structural changes to alteration of cellular processes (C. Balny et al.). II. Revisiting some basic concepts. Pressure-temperature phase diagrams of biomolecules (L. Smeller). The effects of osmotic and hydrostatic pressures on macrom olecular systems (J.A. Kornblatt, M.J. Kornblatt). Compressibility of pr otein transitions (N. Taulier, T.V. Chalikian). Effects of high pressure on enzymatic activity (D.B. Northrop). III. Major developments in experimental methodology. UV-Visible derivative spectroscopy under high pressure (R. Lange, C. Balny). High pressure static fluoresc ence to study macromolecular structure-function (K. Ruan, C. Balny). In vestigations of the effect of high hydrostatic pressure on proteins and lipidic membranes by dynamic fluorescence spectroscopy (P. Tauc et a l.). Tryptophan phosphorescence and pressure effects on protein str ucture (P. Cioni, G.B. Strambini). Fourier transform infrared spectrosco py in high pressure studies on proteins (W. Dzwolak et al.). Hi