In this issue of PET Clinics, guest editors Drs. Stephen Hunt, Steven Feigenberg, and Charles B. Simone bring their considerable expertise to the topic of PET Applications in Radiation Oncology. PET imaging in radiation oncology provides valuable insights into tumor biology, treatment planning, and response assessment. As radiation therapy improves in precision and use, PET-based imaging modalities will become increasingly valuable in the design of radiation treatment fields. In this issue, top experts in the field discuss PET's use in treatment planning, use in certain cancers, and use in reducing radiation-induced injuries.

Contains 10 relevant, practice-oriented topics including integrating PSMA into clinical practice for prostate cancer; current and future radiation oncology applications of PET-based radiomics; updates in the role of PET/CT in radiation oncology in thoracic and gastrointestinal malignancies; the evolving role of PET imaging in assessing vascular and CNS complications of radiation therapy in head and neck cancer; and more. Provides in-depth clinical reviews on PET applications in radiation oncology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.