Point-of-Care Technology for Portable Testing Devices

Point-of-Care Technology for Portable Testing Devices: Nanomaterials-Based Optical Biosensors for Cardiovascular Disease Biomarkers presents various aspects of nanomaterials-based optical biosensing for the detection of cardiovascular disease biomarkers. It begins by classifying cardiac biomarkers based on cardiovascular pathology, exploring tissue specificity, and discussing applications in composite risk prediction models. The subsequent chapters cover the selection of bioreceptors for biosensor systems, an overview of optical nanomaterials, and the design and integration of optical nanobiosensors. Various optical readout techniques, such as colorimetric, fluorescence, chemiluminescence, localized surface plasmon resonance (LSPR), and surface-enhanced Raman scattering (SERS), are examined for their advantages in nanobiosensors. Specific chapters delve into visible and colorimetric nanobiosensors, fluorescence-based nanobiosensors, nanomaterials-based chemiluminescence biosensors, LSPR biosensors, and SERS-based nanobiosensors for cardiovascular disease biomarkers. The book also covers ready-to-use point-of-care testing (PoCT) technologies, advancements in nanobiosensor-based PoCT for cardiovascular biomarkers, and the integration of artificial intelligence in nanomaterials-based optical biosensing. Regulatory and safety considerations for nanomaterials in PoCT applications are discussed, and the final chapter explores advancements in nanomaterials-based point-of-care diagnostic technologies on the path to clinical translation, emphasizing their potential impact on healthcare accessibility and accuracy.