5-Membered Heterocycle Synthesis Using Iodine

5-Membered Heterocycle Synthesis Using Iodine discusses these frameworks which represent the main structural subunits of many biologically active compounds and natural products. The ability of heterocycles to act both as reactive pharmacophores and biomimetics has greatly contributed to their unique value as traditional key elements of various drugs. The contemporary developments in process chemistry and discovery emphasize novel sustainable synthetic pathways as fast and ecologically acceptable alternatives to traditional protocols. As the development of harmless, atom efficient and acid-mediated organic procedures is the most important challenge in green chemistry, this book is a welcomed resource.

While acid catalysis remains the most broadly utilized kind of catalysis, the generally employed acid catalysts continue to pose severe safety and health issues. The mild Lewis acidity of I2 has increased its applicability for many organic reactions.