In the 1920s, Janie McLeary and George King run one of the first movie theatres in the Maritimes. The marriage of the young Irish Catholic woman to an older English man is thought scandalous, but they work happily together, playing music to accompany the films. When George succumbs to illness and dies, leaving Janie with one young child and another on the way, the unscrupulous Joey Elias tries to take over the business.

One night, deceived by the bank manager and Elias into believing she will lose her mortgage, Janie resolves to go and ask for money from the Catholic houses. Elias has sent out men to stop her, so she leaps out the back window and with a broken rib she swims in the dark across the icy Miramichi River, doubting her own sanity.

Astonishingly, she finds herself face to face that night with influential Lord Beaverbrook, who sees in her tremendous character and saves her business. Not only does she survive, she prospers; she becomes wealthy, but ostracized. Even her own father helps Elias plot against her. Yet Janie McLeary King thwarts them and brings first-run talking pictures to the town.

River of the Brokenhearted is a multi-generational epic of rivalries, misunderstandings, rumours; the abuse of power, what weak people will do for love, and the true power of doing right; of a pioneer and her legacy in the lives of her son and grandchildren.