Fungal Pathogenesis: Principles and Clinical Applications

Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens!

This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease.

Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis.

With over 3700 references to accommodate continuing study, Fungal Pathogenesis

covers natural and acquired immunity, vaccine development, and immune reconstitution

outlines rapid identification of major mycoses utilizing antigen capture and molecular assays

details signaling and phenotypic switching

discusses the value of genomics in validation

highlights state-of-the-art molecular methodologies to study disease-causing organisms

describes available and potential antifungal drug targets and drug development

considers predicting the consequences of drug resistance on patient management

presents topical observations on strain typing and variation

and more! Containing research into the virulence, immunity, diagnosis, and therapy of most common fungal infections, Fungal Pathogenesis is an unparalleled reference for microbiologists, virologists, pathologists and phytopathologists, infectious disease specialists, molecular and cell biologists, biochemists, immunologists, medical mycologists, biotechnologists, and geneticists, and an exceptional text for upper-level undergraduate, graduate, and medical school students in these disciplines.