This book begins with an exploration of the relationship between mind and brain. It then examines various psychoanalytic models of the mind and moves to the task of the analyst to discover the unconscious models that shape his or her patients’ picture of him/herself and others.The familiar models are mainly drawn from psychoanalytic practice but are supplemented from myths, religion, and literature. Developments in adjacent scientific fields such as quantum biology and new ideas about evolution are discussed that suggest cellular genetic modification can take place as a consequence of interaction with the outside world. This gives hope perhaps to the idea that not only the mind can learn from experience but also the brain.