Constitutional Genomic Variation in Disease Prediction and Prevention: Breast Cancer explores the molecular basis and impact of a genomic-based personalized approach to breast cancer risk assessment and management in clinical and public healthcare settings. This detailed approach provides a framework for implementing similar clinical assessment and risk-stratified screening programs in different environments. Sections cover Genomic variation and breast cancer risk, Clinical implementation of genome-based breast cancer risk assessments, and Challenges to providing personalized breast cancer risk assessment and management at a population level.

The content assumes no prior knowledge of genomic medicine and provides an educational and practical framework for integrating genomic variant analysis into clinical care in other disease contexts. The book is a valuable resource for cancer researchers, oncologists, clinicians in breast cancer-related specialties, clinical geneticists and several members of biomedical field who are interested in learning about a more personalized approach to treat breast cancer.