Balances depth of detail with clear, readable explanations, providing a concise but comprehensive overview of this complex topic.
An intuitive chapter flow leads with genome organization, gene expression, and RNA processing as a foundation for understanding cellular interactions and cell physiology.
Brings cellular biology to life for students in clinically focused programs, as breakthroughs in areas like gene editing, epigenetics, and the understanding of the microbiome continue to grow in clinical application.
Features unique illustrations with realistic proportions and relationships, including many new instructive illustrations- from structure of volume-regulated LRRC8 Cl -1 channel and generation of circular RNAs from introns . to deadenylation cycles and assembly of SARS CoV-2).
Covers new topics such as optogenetics and super resolution fluorescence microscopy; predicting 3D protein structure; gene expression profiling by single-cell RNA sequencing; protein misfolding and human disease; mechanism of CFTR and new drugs to treat cystic fibrosis; new insights on carriers and channels and their clinical implications; mitochondrial genomes from sperm; and biogenesis of lipid droplets and lipid transfer between organelles.
Uses real examples to illustrate key cell biology concepts, includes beneficial cell physiology coverage, and relates cell biology to pathophysiology and medicine.
Clear, readable explanations provide a concise story about how cells function at the molecular level.
An intuitive chapter flow starts with genome organization, gene expression, and RNA processing as a foundation for understanding every aspect of cellular function and physiology.
Brings cellular biology to life for students interested in medical science by explaining how mutations in genes can compromise virtually every cellular system and predispose to human disease. Knowledge of cell biology has led to new treatments for cancer, heart failure, cystic fibrosis, and many other diseases.
Unique illustrations with realistic proportions and relationships explain every cellular process including the assembly of SARS CoV-2, the structures attaching mitotic chromosomes to microtubules, the mechanism of DNA replication and how pumps, carriers and channels orchestrate physiological processes from synaptic transmission to cellular volume regulation.
Covers exciting breakthroughs such as SMC motor proteins actively organizing chromosomal DNA, TOR kinases regulating metabolism, new types of immunotherapy for cancer treatment, mechanisms regulating fast axonal transport and their relation to neurodegenerative diseases, how completion of DNA replication sets the time for cells to enter mitosis, how a cascade of signals specifies the site of cell division, and newly understood pathways of normal and pathological cell death.
