U.S.-Europe Collaboration in Space Science reviews the past 30 years of space-based research across the Atlantic. The book, which was prepared jointly with the European Space Science Committee (under the aegis of the European Science Foundation) begins with a broad survey of the historical and political context of U.S.-Europe cooperation and collaboration in space. The focus of the book is a set of 13 U.S.-Europe missions in astrophysics, space physics, planetary sciences, earth sciences, and life and microgravity research that illustrate lessons learned on the evolution of the cooperation, mission planning and scheduling, international agreements, cost-sharing, management, and scientific output. These lessons form the basis of the joint committee’s findings and recommendations, which serve to improve the future conduct and enhance the scientific output of U.S.-Europe cooperation and collaboration in space science.