Nuclear Envelope Dynamics in Embryos and Somatic Cells

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This volume provides a review of the most current knowledge of the composition, architecture and dynamics of the nuclear envelope. Experts in the field relate the different domains of the nuclear envelope, their biogenesis, their composition, their mode of targeting to chromosomes and how they dissociate from chromosomes upon cell division. A wealth of information from several experimental systems is provided, such as dividing somatic cells, embryos and nuclear assembly assays in cell-free extracts, in a wide range of vertebrate and invertebrate organisms ranging from humans to yeast. This book also contains reviews on the relationship between mutations in proteins of the nuclear envelope and Emery-Dreifuss muscular dystrophy.