Rational Design of Stable Protein Formulations: Theory and Practice
Rational Design of Stable Protein Formulations: Theory and Practice
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Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today’s pharmaceutical industry. Our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach the formulation of protein pharmaceuticals from a much more rational point of view. This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.
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