Noninvasive Assessment of Trabecular Bone Architecture and The Competence of Bone

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The study of bone microarchitecture is flourishing because of a shift in perspective that has taken researchers beyond utilizing bone mineral density as the primary source of information about certain matters related to bone. In the area of osteoporosis and skeletal changes, bone mineral density (BMD) is widely used for screening, monitoring and assessing therapeutic efficacy, and yet, it is currently accepted that BMD does not fully explain the pathogenesis of osteoporosis, the process of ageing, nor mechanisms of therapeutic efficacy. In this context, the study of trabecular microarchitecture has much to contribute. The emerging field of trabecular microarchitecture, however, is diverse, interdisciplinary and encompasses many different imaging modalities. This volume represents a compilation of papers from various researchers, reflecting contemporary research in the area of noninvasive assessment of trabecular microcarchitecture. These varied papers apply sophisticated imaging tools to questions of bone biomechanics at both the basic science and clinical levels. The authors’ works range from review articles and research articles to works in progress. Taken together, they offer a foray into the state of the art of investigating bone at its most basic levels.