To date there is no one method for treating spina bifida, one of the most common anomalies in the nervous system. With a recurrence rate of ten percent, managing spina bifida cases requires a multidisciplinary approach involving several medical and surgical specialties. This collection of papers takes a clinical management approach to the multidisciplinary problem of spina bifida. The leading neurosurgery, orthopedics, urology, and allied health experts from major American children’s hospitals explore topics in etiology, epidemiology, prenatal diagnosis, and rehabilitation.