Calvet’s Web is a study of the correspondence network of an Avignon physician in the period 1750-1810. Esprit Calvet was an antiquarian, natural historian, and bibliophile, and was at the centre of a circle of like-minded intellectuals from various backgrounds, chiefly based in the Rhone valley. Laurence Brockliss explores for the first time in detail the intellectual interests and relationships of a representative sample of the French Republic of Letters. He traces the destruction of the Republic during the Revolution, and its reconstruction, in different guise, under Napoleon. Calvet’s Web is an important contribution to our understanding of the social construction of knowledge, the history of collecting, and the history of the book. In addition, by examining the circle’s attitude to the philosophes and their programme of material and moral progress, it offers a new picture of the relationship between the Republic of Letters and the Enlightenment.