Plato and Aristotle were very much alive between the fifteenth and the seventeenth centuries. The essays in this volume investigate the interaction, both in terms of harmony and contrast, between the two philosophers in early modernity, that is in a time when long-forgotten texts became available and a new philological awareness was on the rise. Dealing with famous and less famous early modern interpreters and philosophers, in a transnational and translinguistic perspective, this volume reveals the agendas behind the discussions on Plato’s and Aristotle’s philosophies. In studying these texts, it is hard to imagine a more significant collision of big names with big ideas. This project takes us to the centre of the intellectual life of the period and its most exciting debates.