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This volume provides research level information for a wide variety of scientists working on molecular aspects of protein phosphorylation in cancer and cell biology, developmental biology and genetics. It concentrates on the ever-increasing number of animal kinases, but also include examples of Drosophila, yeast Dictyostelium and more. The text provides information on subnit structure and isoforms; genetics; sequence database accession numbers; domain structures; amino acid sequences; homologues in other species; patterns of expression; physiological substrates and specificity determinants; assays; and enzyme activator inhibitors.
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This volume provides research level information for a wide variety of scientists working on molecular aspects of protein phosphorylation in cancer and cell biology, developmental biology and genetics. It concentrates on the ever-increasing number of animal kinases, but also include examples of Drosophila, yeast Dictyostelium and more. The text provides information on subnit structure and isoforms; genetics; sequence database accession numbers; domain structures; amino acid sequences; homologues in other species; patterns of expression; physiological substrates and specificity determinants; assays; and enzyme activator inhibitors.