Angels is the story of two born losers. Jamie is escaping with two baby girls from a husband who has gone zombie-like on her. Bill is dreaming of making it big in a life of crime so natural to him that any other way would make no sense. They meet on a Greyhound bus, and team up because they have nowhere else to go. So begins a stunning, tragic odyssey through the dark flipside of America - the bars, bus stations, mental wards and prisons of the legions of the lost where Jamie and Bill travel on their inevitable downward spiral though rape, alcohol, drugs and crime to madness and death.