The lab manual was written and classroom-tested by the authors of the text. It has been revised in recent editions to emphasize a more inquiry-oriented approach and to increase the number of biology labs. Each lab begins with an open-ended Invitations to Inquiry, designed to peak student interest in the lab concept. This is followed by laboratory exercises that require measurement and data analysis for work in a more structured learning environment. When the laboratory manual is used with Integrated Science text, students will have an opportunity to understand the nature of scientific inquiry from the perspective of hands-on experiences in order to master basic scientific principles and concepts and learn new problem-solving and thinking skills. There is also an instructor’s edition lab manual available for instructors on ARIS and the ITR CD.