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      Cover image for The Future of Home Health Care: Workshop Summary
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      The Future of Home Health Care: Workshop Summary

      National Research Council,Institute of Medicine,Division on Behavioral and Social Sciences and Education,Board on Health Sciences Policy,Forum on Aging, Disability, and Independence

      Individuals with disabilities, chronic conditions, and functional impairments need a range of services and supports to keep living independently. However, there often is not a strong link between medical care…

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      Cover image for Stem Cell Therapies: Opportunities for Ensuring the Quality and Safety of Clinical Offerings: Summary of a Joint Workshop by the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research
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      Stem Cell Therapies: Opportunities for Ensuring the Quality and Safety of Clinical Offerings: Summary of a Joint Workshop by the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research

      National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy

      Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body’s intrinsic repair mechanisms, stem cells…

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      Cover image for Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research
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      Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research

      Committee on Health Research and the Privacy of Health Information: The HIPAA Privacy Rule,Institute of Medicine

      In the realm of health care, privacy protections are needed to preserve patients’ dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines…

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      Cover image for Enhancing Scientific Reproducibility in Biomedical Research Through Transparent Reporting: Proceedings of a Workshop
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      Enhancing Scientific Reproducibility in Biomedical Research Through Transparent Reporting: Proceedings of a Workshop

      National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Board on Health Sciences Policy,Roundtable on Genomics and Precision Health

      Sharing knowledge is what drives scientific progress - each new advance or innovation in biomedical research builds on previous observations. However, for experimental findings to be broadly accepted as credible…

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      Cover image for Strengthening the Disaster Resilience of the Academic Biomedical Research Community: Protecting the Nation's Investment
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      Strengthening the Disaster Resilience of the Academic Biomedical Research Community: Protecting the Nation’s Investment

      National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Health and Medicine Division,Institute for Laboratory Animal Research,Board on Earth Sciences and Resources

      The academic biomedical research community is a hub of employment, economic productivity, and scientific progress. Academic research institutions are drivers of economic development in their local and state economies and…

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      Cover image for Mapping the Brain and Its Functions: Integrating Enabling Technologies into Neuroscience Research
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      Mapping the Brain and Its Functions: Integrating Enabling Technologies into Neuroscience Research

      Institute of Medicine,Division of Biobehavioral Sciences and Mental Disorders,Division of Health Sciences Policy,Committee on a National Neural Circuitry Database

      Featuring color photography, this book presents an overview of the complexity of brain research, which covers the spectrum from human behavior to genetic mechanisms. Advances in vision, substance abuse, pain…

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      Cover image for Examining the Health Disparities Research Plan of the National Institutes of Health: Unfinished Business
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      Examining the Health Disparities Research Plan of the National Institutes of Health: Unfinished Business

      Committee on the Review and Assessment of the NIH's Strategic Research Plan and Budget to Reduce and Ultimately Eliminate Health Disparities,National Academy of Sciences

      This review of the National Institute of Health (NIH) plan to reduce health disparities among racial and ethnic minorities was undertaken by experts chosen by the National Research Council. The…

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      Cover image for Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches: Workshop Summary
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      Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches: Workshop Summary

      LeighAnne Olsen,J. Michael McGinnis,Roundtable on Value & Science-Driven Health Care,Institute of Medicine

      Recent scientific and technological advances have accelerated our understanding of the causes of disease development and progression, and resulted in innovative treatments and therapies. Ongoing work to elucidate the effects…

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      Cover image for Direct-to-Consumer Genetic Testing: Summary of a Workshop
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      Direct-to-Consumer Genetic Testing: Summary of a Workshop

      Committee on Science, Technology, and Law,Forum on Drug Discovery, Development, and Translation,Roundtable on Translating Genomic-Based Research for Health,National Research Council,Institute of Medicine

      Today, scores of companies, primarily in the United States and Europe, are offering whole genome scanning services directly to the public. The proliferation of these companies and the services they…

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      Cover image for BioWatch and Public Health Surveillance: Evaluating Systems for the Early Detection of Biological Threats: Abbreviated Version
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      BioWatch and Public Health Surveillance: Evaluating Systems for the Early Detection of Biological Threats: Abbreviated Version

      Committee on Effectiveness of National Biosurveillance Systems: BioWatch and the Public Health System,National Research Council

      Following the attacks of September 11, 2001 and the anthrax letters, the ability to detect biological threats as quickly as possible became a top priority. In 2003 the Department of…

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      Cover image for Fostering Independence, Participation, and Healthy Aging Through Technology: Workshop Summary
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      Fostering Independence, Participation, and Healthy Aging Through Technology: Workshop Summary

      National Research Council,Institute of Medicine,Division of Behavioral and Social Sciences and Education,Board on Health Sciences Policy,Forum on Aging, Disability, and Independence

      The Institute of Medicine (IOM) and the National Research Council (NRC) have had prominent roles in discussions of aging, disability, and technology for decades. In 1978, Aging and Medical Education…

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      Cover image for Necessity, Use, and Care of Laboratory Dogs at the U.S. Department of Veterans Affairs
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      Necessity, Use, and Care of Laboratory Dogs at the U.S. Department of Veterans Affairs

      National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Division on Earth and Life Studies,Institute for Laboratory Animal Research

      For many years, laboratory dogs have served as important animal models for biomedical research that has advanced human health. Conducted at the request of the U.S. Department of Veterans Affairs…

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      Cover image for Digital Data Improvement Priorities for Continuous Learning in Health and Health Care: Workshop Summary
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      Digital Data Improvement Priorities for Continuous Learning in Health and Health Care: Workshop Summary

      Institute of Medicine,Roundtable on Value and Science-Driven Health Care

      Digital health data are the lifeblood of a continuous learning health system. A steady flow of reliable data is necessary to coordinate and monitor patient care, analyze and improve systems…

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      Cover image for Health Literacy in Clinical Research: Practice and Impact: Proceedings of a Workshop
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      Health Literacy in Clinical Research: Practice and Impact: Proceedings of a Workshop

      National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Roundtable on Health Literacy

      Because of the individualized nature of drug and therapeutic treatments, clinical trials require participants who represent the diversity of the patient base. If early trials do not have a broad…

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      Cover image for Observational Studies in a Learning Health System: Workshop Summary
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      Observational Studies in a Learning Health System: Workshop Summary

      Institute of Medicine,Roundtable on Value and Science-Driven Health Care,A Learning Health System Activity

      Clinical research strains to keep up with the rapid and iterative evolution of medical interventions, clinical practice innovation, and the increasing demand for information on the clinical effectiveness of these…

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      Cover image for Integrating Research and Practice: Health System Leaders Working Toward High-Value Care: Workshop Summary
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      Integrating Research and Practice: Health System Leaders Working Toward High-Value Care: Workshop Summary

      IOM Roundtable on Value & Science-Driven Care,Institute of Medicine

      Health care has been called one of the most complex sectors of the U.S. economy. Driven largely by robust innovation in treatments and interventions, this complexity has created an increased…

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      Cover image for Nonhuman Primate Models in Biomedical Research
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      Nonhuman Primate Models in Biomedical Research

      National Academies of Sciences, Engineering, and Medicine, Division on Earth and Life Studies, Health and Medicine Division, Institute for Laboratory Animal Research, Board on Health Sciences Policy, Committee on the State of the Science and Future Needs for Nonhuman Primate Model Systems

      Nonhuman primates represent a small fraction of animals used in biomedical research, but they remain important research models due to their similarities to humans with respect to genetic makeup, anatomy…

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      Cover image for Ovarian Cancers: Evolving Paradigms in Research and Care
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      Ovarian Cancers: Evolving Paradigms in Research and Care

      National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on the State of the Science in Ovarian Cancer Research

      In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian…

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      Cover image for International Animal Research Regulations: Impact on Neuroscience Research: Workshop Summary
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      International Animal Research Regulations: Impact on Neuroscience Research: Workshop Summary

      National Research Council,Institute of Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Policy and Global Affairs

      Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders…

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      Cover image for Facing the Reality of Drug-Resistant Tuberculosis in India: Challenges and Potential Solutions: Summary of a Joint Workshop by the Institute of Medicine, the Indian National Science Academy, and the Indian Council of Medical Research
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      Facing the Reality of Drug-Resistant Tuberculosis in India: Challenges and Potential Solutions: Summary of a Joint Workshop by the Institute of Medicine, the Indian National Science Academy, and the Indian Council of Medical Research

      Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

      An estimated 8.8 million people fell ill with tuberculosis (TB) in 2010 and 1.4 million died from the disease. Although antibiotics to treat TB were developed in the 1950s and…

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      Cover image for Breast Cancer and the Environment: A Life Course Approach
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      Breast Cancer and the Environment: A Life Course Approach

      Committee on Breast Cancer and the Environment: The Scientific Evidence, Research Methodology, and Future Directions,Institute of Medicine

      Breast cancer remains the most common invasive cancer among women. The primary patients of breast cancer are adult women who are approaching or have reached menopause; 90 percent of new…

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      Cover image for Pan-Organizational Summit on the U.S. Science and Engineering Workforce: Meeting Summary
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      Pan-Organizational Summit on the U.S. Science and Engineering Workforce: Meeting Summary

      Government-University-Industry Research Roundtable,National Academy of Sciences,Policy and Global Affairs,National Academy of Engineering,Marye Anne Fox, Ph.D.

      Each of 32 nonprofit organizations contributing a presentation to the Pan-Organizational Summit on the Science and Engineering Workforce was invited to issue a corresponding position paper to be reproduced in…

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      Cover image for Opportunities to Address Clinical Research Workforce Diversity Needs for 2010
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      Opportunities to Address Clinical Research Workforce Diversity Needs for 2010

      Committee on Opportunities to Address Clinical Research Workforce Diversity Needs for 2010,Committee on Women in Science and Engineering,National Research Council

      Based on a 2003 workshop, this study describes current public and private programs and recommends ways to recruit and retain more women and underrepresented minorities into clinical research, especially physician-scientists…

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      Cover image for Hearing Loss and Healthy Aging: Workshop Summary
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      Hearing Loss and Healthy Aging: Workshop Summary

      Forum on Aging, Disability, and Independence,Board on Health Sciences Policy,Division on Behavioral and Social Sciences and Education

      Being able to communicate is a cornerstone of healthy aging. People need to make themselves understood and to understand others to remain cognitively and socially engaged with families, friends, and…

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      Cover image for Potential Risks and Benefits of Gain-of-Function Research: Summary of a Workshop
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      Potential Risks and Benefits of Gain-of-Function Research: Summary of a Workshop

      National Research Council,Institute of Medicine,Board on Health Sciences Policy,Policy and Global Affairs,Committee on Science, Technology, and Law

      On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy…

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      Cover image for Digital Infrastructure for the Learning Health System: The Foundation for Continuous Improvement in Health and Health Care: Workshop Series Summary
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      Digital Infrastructure for the Learning Health System: The Foundation for Continuous Improvement in Health and Health Care: Workshop Series Summary

      Roundtable on Value & Science-Driven Health Care,Institute of Medicine,Institute of Medicine

      Like many other industries, health care is increasingly turning to digital information and the use of electronic resources. The Institute of Medicine’s Roundtable on Value & Science-Driven Health Care hosted…

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      Cover image for Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research: Workshop Report
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      Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research: Workshop Report

      Committee on Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research,National Research Council

      Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research

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      Cover image for Transforming Clinical Research in the United States: Challenges and Opportunities: Workshop Summary
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      Transforming Clinical Research in the United States: Challenges and Opportunities: Workshop Summary

      Rebecca English,Yeonwoo Lebovitz,Robert Griffin,Forum on Drug Discovery, Development, and Translation,Institute of Medicine

      An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications…

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      Cover image for Chimpanzees in Biomedical and Behavioral Research: Assessing the Necessity
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      Chimpanzees in Biomedical and Behavioral Research: Assessing the Necessity

      Committee on the Use of Chimpanzees in Biomedical and Behavioral Research,National Research Council

      For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate…

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      Cover image for Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine: Proceedings of a Workshop
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      Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine: Proceedings of a Workshop

      National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

      Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of…

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      Cover image for Confronting AIDS: Directions for Public Health, Health Care and Research
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      Confronting AIDS: Directions for Public Health, Health Care and Research

      Committee on a National Strategy for AIDS,Institute of Medicine,National Academy of Sciences

      Examines the complex medical, social, ethical, financial, and scientific problems arising from the AIDS epidemic. This book also offers several public policy and research recommendations for an appropriate national response…

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      Cover image for Core Measurement Needs for Better Care, Better Health, and Lower Costs: Counting What Counts: Workshop Summary
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      Core Measurement Needs for Better Care, Better Health, and Lower Costs: Counting What Counts: Workshop Summary

      Institute of Medicine,Roundtable on Value and Science-Driven Health Care

      In 2006 the Institute of Medicine (IOM) established the Roundtable on Value & Science-Driven Health Care which has since accelerated the development of a learning health system- one in which…

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      Cover image for Patients Charting the Course: Citizen Engagement in the Learning Health System: Workshop Summary
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      Patients Charting the Course: Citizen Engagement in the Learning Health System: Workshop Summary

      Institute of Medicine,Institute of Medicine

      As past, current, or future patients, the public should be the health care system’s unwavering focus and serve as change agents in its care. Taking this into account, the quality…

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      Cover image for Toward Health Equity and Patient-Centeredness: Integrating Health Literacy, Disparities Reduction, and Quality Improvement: Workshop Summary
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      Toward Health Equity and Patient-Centeredness: Integrating Health Literacy, Disparities Reduction, and Quality Improvement: Workshop Summary

      Roundtable on Health Disparities,Forum on the Science of Health Care Quality Improvement and Implementation

      To receive the greatest value for health care, it is important to focus on issues of quality and disparity, and the ability of individuals to make appropriate decisions based on…

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      Cover image for Women and Health Research: Ethical and Legal Issues of Including Women in Clinical Studies
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      Women and Health Research: Ethical and Legal Issues of Including Women in Clinical Studies

      Committee on the Ethical and Legal Issues Relating to the Inclusion of Women in Clinical Studies,Institute of Medicine

      Addresses issues connected with women’s participation in clinical studies: ethical issues related to recruitment, retention, and the inclusion of pregnant women and other women of childbearing age; legal issues such…

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      Cover image for Safe and Effective Medicines for Children: Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act
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      Safe and Effective Medicines for Children: Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act

      Committee on Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA),Institute of Medicine

      The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the…

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      Cover image for Injury in America: A Continuing Public Health Problem
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      Injury in America: A Continuing Public Health Problem

      Committee on Trauma Research,Commission on Life Sciences,Institute of Medicine,Division on Earth and Life Studies,National Research Council

      Provides a survey of what is known about injuries, and suggests that there is a vast need to know more. This book traces findings on the epidemiology of injuries, prevention…

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      Cover image for Focusing on Children's Health: Community Approaches to Addressing Health Disparities: Workshop Summary
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      Focusing on Children’s Health: Community Approaches to Addressing Health Disparities: Workshop Summary

      Roundtable on Health Disparities,Institute of Medicine,National Research Council

      Socioeconomic conditions are known to be major determinants of health at all stages of life, from pregnancy through childhood and adulthood. Life-course epidemiology has added a further dimension to the…

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      Cover image for Achieving Health Equity via the Affordable Care Act: Promises, Provisions, and Making Reform a Reality for Diverse Patients: Workshop Summary
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      Achieving Health Equity via the Affordable Care Act: Promises, Provisions, and Making Reform a Reality for Diverse Patients: Workshop Summary

      National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Population Health and Public Health Practice,Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities

      Since its creation by the Institute of Medicine (IOM) in 2007, the Roundtable on the Promotion of Health Equity and the Elimination of Health Disparities has been fostering dialogue on…

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      Cover image for Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research: Proceedings of a Workshop
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      Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research: Proceedings of a Workshop

      National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

      The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a…

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      Cover image for Stem Cells and the Future of Regenerative Medicine
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      Stem Cells and the Future of Regenerative Medicine

      Committee on the Biological and Biomedical Applications of Stem Cell Research,Commission on Life Sciences,National Research Council,Board on Neuroscience and Behavioral Health,Institute of Medicine

      Provides an exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. This book also presents an overview of the moral and ethical…

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      Cover image for Mining Safety and Health Research at NIOSH: Reviews of Research Programs of the National Institute for Occupational Safety and Health
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      Mining Safety and Health Research at NIOSH: Reviews of Research Programs of the National Institute for Occupational Safety and Health

      Committee to Review the NIOSH Mining Safety and Health Research Program,Committee on Earth Resources,National Research Council,National Academy of Sciences

      Rpt. no. 2, Reviews of research programs of the National Institute for Occupational Safety and Health –T.p. verso.

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      Cover image for Preventing Intimate Partner Violence in Uganda, Kenya, and Tanzania: Summary of a Joint Workshop by the Institute of Medicine, the National Research Council, and the Uganda National Academy of Sciences
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      Preventing Intimate Partner Violence in Uganda, Kenya, and Tanzania: Summary of a Joint Workshop by the Institute of Medicine, the National Research Council, and the Uganda National Academy of Sciences

      National Research Council,Institute of Medicine,Board on Global Health,Forum on Global Violence Prevention

      Globally, between 15-71 percent of women will experience physical and/or sexual abuse from an intimate partner at some point in their lifetime. Too often this preventable form of violence is…

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      Cover image for Animal Models for Microbiome Research: Advancing Basic and Translational Science: Proceedings of a Workshop
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      Animal Models for Microbiome Research: Advancing Basic and Translational Science: Proceedings of a Workshop

      National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

      The surface of the human body and its mucous membranes are heavily colonized by microorganisms. Our understanding of the contributions that complex microbial communities make to health and disease is…

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      Cover image for Design, Implementation, Monitoring, and Sharing of Performance Standards for Laboratory Animal Use: Summary of a Workshop
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      Design, Implementation, Monitoring, and Sharing of Performance Standards for Laboratory Animal Use: Summary of a Workshop

      National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Roundtable on Science and Welfare in Laboratory Animal Use

      In order to better understand the critical issues pertaining to the concept of performance standards for laboratory animal use, the Institute for Laboratory Animal Research Roundtable on Science and Welfare…

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      Cover image for A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA's Bioastronautics Roadmap
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      A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap

      Board on Health Sciences Policy,Committee on Review of NASA's Bioastronautics Roadmap,National Research Council,Aeronautics and Space Engineering Board,Space Studies Board

      A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap (2006)

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      Cover image for John R. La Montagne Memorial Symposium on Pandemic Influenza Research: Meeting Proceedings
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      John R. La Montagne Memorial Symposium on Pandemic Influenza Research: Meeting Proceedings

      Institute of Medicine,Board on Population Health and Public Health Practice,Planning Group on the John R. La Montagne Memorial Symposium on Pandemic Influenza Research,National Academy of Sciences

      The Institute of Medicine (IOM) of the National Academies of Science held a symposium, in memory of Dr. John R. La Montagne on April 4-5, 2005, to discuss the current…

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      Cover image for The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research
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      The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research

      Institute of Medicine,Board on Health Sciences Policy,Committee to Review the Clinical and Translational Science Awards Program at the National Center for Advancing Translational Sciences

      In 2006 the National Institutes of Health (NIH) established the Clinical and Translational Science Awards (CTSA) Program, recognizing the need for a new impetus to encourage clinical and translational research…

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