Since its founding in 1982, the Small Business Innovation Research (SBIR) program has become the largest and most comprehensive public research and development funding program of small business research in…

This final report contains the full contents of Optimizing the Nation’s Investment in Academic Research: A New Regulatory Framework for the 21st Century: Part 1, which was initially released as…

Research and innovation in the life sciences is driving rapid growth in agriculture, biomedical science, information science and computing, energy, and other sectors of the U.S. economy. This economic activity…

The United States has long recognized that the nation’s prosperity and security depend on how we address challenges of disasters, poverty, famine, and disease around the world. The U.S. Agency…

Technological advances in noninvasive neuroimaging, neurophysiology, genome sequencing, and other methods together with rapid progress in computational and statistical methods and data storage have facilitated large-scale collection of human genomic…

Climate change is creating impacts that are widespread and severe for individuals, communities, economies, and ecosystems around the world. While efforts to reduce emissions and adapt to climate impacts are…

The ability of the nation’s military to prevail during future conflicts, and to fulfill its humanitarian and other missions, depends on continued advances in the nation’s technology base. A workforce…

Biomedical research results in the collection and storage of increasingly large and complex data sets. Preserving those data so that they are discoverable, accessible, and interpretable accelerates scientific discovery and…