Telemedicine has the potential to improve access to health care, particularly in areas where there are geographical barriers, as well as to reduce costs. Telemedicine may take more time to face challenges in connecting virtual communication due to a slow internet connection or a server malfunction. The advancement and integration of information and communication technologies into healthcare delivery hold enormous promise for patients, providers, and payers in future healthcare systems. This Review Book, is overview of Telemedicine is discussed, which includes applications of Telemedicine, handling and protecting the data, diagnosis process and more things.