This book celebrates Professor Shu Chien’s contributions and achievements in his eight decades of learning, servicing, innovation and creation. The book is composed of tributes written by family, friends, colleagues, students, and trainees, as well as an autobiography by Professor Chien.Professor Chien is one of the most eminent scientists in the world. He is a laureate of US National Medal of Science and Taiwan’s Presidential Prize in Life Sciences, as well as members of six American and Chinese Academies. Besides his academic achievements in physiology and biomedical engineering, he has made outstanding contributions through leadership in professional organizations in these disciplines. His dedications to education and teaching have inspired countless young scientists around the world. The tribute articles written by family, friends, colleagues, students, and trainees, together with memorable photographs, provide an excellent summary of how this remarkable person is viewed by others. Professor Chien’s autobiography presents his illustrious life history and shares his precious experience and philosophy, resonating with the tributes by others. This book makes a very enjoyable and inspirational reading to everyone.