This publication has been developed based on the results of the Technical Meeting on Advances in Post-Irradiation Examination Techniques for Power-Reactor Irradiated Fuels and Innovative Fuels held in July 2021. It explores the use of existing and new post-irradiation examination (PIE) techniques for the study of next-generation fuel types. Specifically, this publication provides an overall understanding of what important performance parameters are typically studied for each fuel type to properly assess its performance, and what are the relevant PIE techniques required for the analyses. Its intended audience comprises nuclear fuel designers, manufacturers, operators, regulators, academia and policy makers who work with the nuclear fuel community.