This Safety Report explains how the concepts of attribution of health effects and inference of risks can be taken into account in the application of IAEA safety standards, so as to implement them more effectively. In particular, this publication demonstrates explicitly what the relevant provisions of the safety standards are for high and moderate levels of exposure where health effects might be able to be attributed to the exposure, and for low and very low levels of exposure where risks can only be inferred. This Safety Report also aims to support more effective communication by clarifying the proper use of certain concepts detailed in the safety standards and plain language explanations of the concepts of attribution of effects and inference of risk are provided.