This publication is the outcome of a meeting of an international team of experts that discussed various technical and scientific details applicable to the production of important radionuclides such as 99Mo, copper-67 (67Cu), scandium-47 (47Sc) and actinium-225 (225Ac) using the photonuclear route. This publication provides an overview of the current state of methods for the photonuclear production of isotopes with a particular focus on those medical radioisotopes that could be produced in sufficient quantities for clinical use in nuclear medicine. It is intended for scientists and technical professionals in the fields of electron accelerators and radioisotope production