The IAEA recognizes the importance of food safety to Member States and that laboratories are the fulcrum of a reliable food safety control system, without which, routine testing and monitoring of chemical and related hazards would remain a challenge. The IAEA and the Food and Agricultural Organization of the United Nations (FAO), through the Joint FAO/IAEA Centre of Nuclear Techniques in Food and Agriculture, help scientists to enhance the performance of laboratories and contribute to safeguarding consumer health as well as promoting the market competitiveness of foodstuff such as aquaculture products. Aquaculture is one of the fastest growing food-production sectors in the world and requires urgent attention. This publication presents several analytical methods including an annex of standard operating procedures, for testing residues of chemicals including veterinary drugs and selected contaminants in aquaculture products and production environments. This publication is intended for regulatory as well as research and academic food safety and control institutions.