This publication represents a general consensus among participating experts of the best common practices that can be used at nuclear power plants (NPPs) in reload design and core management. It outlines the main issues to be considered when developing and improving reload design and core management and presents lessons learned, as well as detailing challenges which may be encountered. Guidance provided here also covers best practice for different reload strategies and how to optimize reactor reload design and core management during the lifetime of a NPP. The publication reflects the advice of experts with experience of reactors of various types on how the operating organization may achieve its goals.