This volume examines the rise and apparent fall of ‘neo-liberalism’, whose historical roots and theoretical implications are explored throughout. This begins with today’s current climate, dominated by a range of political mediatic populisms that run across the contemporary political scene, and a critical comparison with the seminal analysis of Ernesto Laclau. The volume also analyzes the failure of the multicultural paradigm in terms of the Lockean concept of tolerance in light of the theses developed by the political theorist Wendy Brown concerning the civil and social dynamics of de-democratization. From this point of view, an original concept of post-hegemony is proposed, which - attempting to go beyond Antonio Gramsci and his modern followers - focuses on the subject of desire and enjoyment within a Freudian and Lacanian framework, a subject whose drives are incompatible with the systemic grid of contemporary hyper-capitalism. Finally, following a provocative analysis of violence and terrorism in the globalized world, the volume proposes - on the basis of Judith Butler’s analysis - a paradigm of a democracy of bodies as an alternative to and salvation from the decline of the political in the present era.