Natural products of various origins, whether plant or animal, have been playing an important role in different sectors of the industry, such as pharmaceuticals, because some of these substances act beneficially in the fight against various diseases, such as those of inflammatory origin and even cancer. Many hypotheses are based on the action of these compounds in modulating the inflammatory response, making them effective in the proposed effect, as well as preventing the installation of tissue damage, a recurring fact in exacerbated inflammatory responses. Among the natural products with therapeutic potential are polyunsaturated fatty acids, which have shown efficacy in their proposed effect, but because their metabolism is hepatic, they present serious restrictions due to the induction of hepatotoxicity. This book presents the anti-inflammatory potential of pure and microemulsified bullfrog oil based on research carried out in a sepsis model. To this end, the author of this book invites you to enjoy an easy-to-understand and very enlightening reading about bullfrog oil and its anti-inflammatory properties.