Role of Platelet Concentrate in Periodontology and Implantology

Aishwarya Mittal, Nancy Srivastava, Neetha Bhargava

Format
Paperback
Publisher
LAP Lambert Academic Publishing
Published
24 July 2024
Pages
276
ISBN
9786207648382

Role of Platelet Concentrate in Periodontology and Implantology

Aishwarya Mittal, Nancy Srivastava, Neetha Bhargava

Platelet concentrates play a crucial role in periodontal regeneration. They are prepared from the patient's own blood, where activated platelets are enclosed within a fibrin matrix scaffold and release growth factors and cytokines that play a key role in tissue regeneration. This includes cell proliferation and differentiation, extracellular matrix synthesis, chemotaxis, and angiogenesis. Platelets have been confirmed to aid in regeneration due to their pool of growth factors that are responsible for neovascularization, collagen synthesis, cell division, cell differentiation, induction, and migration of other cells to the injured site. They contain fibrin, fibronectin, and vitronectin that contribute to connective tissue, a matrix, and create an efficient network for cell migration.In implantology, platelet concentrates significantly improve implant stability and reduce marginal bone loss in the short term. They enhance osseointegration, which is essential for the success and stability of implants. they aids in tissue regeneration, wound healing, and improving implant stability, thus offering a promising avenue for future research and clinical applications in these fields.

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