Gynecological cancer is the fourth most common type worldwide; the steep rise in chronic illnesses constitutes a public health challenge for health services and policymakers. The diagnosis of cancer affects patients and their families physically, financially, and emotionally. Cancer is still considered synonymous with death, pain, and suffering. Therefore, there is a need for attempts toward enhancing the physical performance and quality of life of this category of patients. The oncology nurse has an important role in patient education and managing side effects, thereby helping each woman maintain her sexuality and quality of life.