Artesunate is a drug derived from artemisinin used to treat the most aggressive form of malaria. However, its use is not recommended in the first trimester of pregnancy due to its toxic effects on the embryo's reproductive tract. This reproductive toxicity may be related to the oestrogenic action of this drug. Despite the evidence of artesunate's oestrogenic action, no studies have yet been carried out on the subject. And this is what this book presents in greater depth.