Hospital readmissions constitute a relevant problem for health services, hospital institutions and patients due to their impact on morbidity and mortality, and the province of Santi Spiritus does not escape this problem. With the general objective of characterizing hospital readmission in patients with chronic non-communicable diseases in the General Hospital Camilo Cienfuegos of Santi Spiritus from 2021 to 2022, an observational, descriptive, prospective and cross-sectional study was carried out in a population of 126 patients according to the research criteria: age, sex, chronic non-communicable diseases, risk factors, cause of readmission and time of occurrence of readmission were assumed as variables.The population showed a mean age of 66.19 years for the male sex and 70.38 years for the female sex.The causes of hospital readmission were mainly: complications of the previous admission, recurrence of the disease, poor therapeutic compliance and appearance of a new disease.The patients were readmitted in less than one month.