Conhecendo o Zika virus
Daniel Campos,Jonas Oliveira
Conhecendo o Zika virus
Daniel Campos,Jonas Oliveira
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A infeccao reemergente pelo Zika virus (ZIKV) se tornou uma ameaca a saude global devido a associacao com anormalidades neurologicas graves, sendo elas a sindrome de Guillain-Barre (SGB) em adultos e a sindrome congenita do Zika virus (SCZ) em neonatos. Muitas pesquisas de desenvolvimento e inovacao objetivam um composto antiviral eficaz contra o ZIKV, mas ate o momento, nao ha nenhum composto comercialmente disponivel. Com o objetivo de elucidar os avancos sobre a infeccao pelo ZIKV, esta revisao enfatiza os estudos realizados apos o surto ocorrido no Brasil entre 2015 e 2016, descrevendo o que ha de mais novo sobre a epidemiologia, transmissao, replicacao viral, sintomatologia clinica, diagnostico laboratorial e radiologico, tratamento, prevencao e alvos de medicamento antiviral para o desenvolvimento de farmacos anti-Zika.
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