Toxicidade e mecanismo de acao sobre leveduras e dermatofitos

Maysa Paula Da Costa Reis, Maria R R Silva, Carolina R Costa

Toxicidade e mecanismo de acao sobre leveduras e dermatofitos
Format
Paperback
Publisher
Novas Edicoes Academicas
Published
15 January 2019
Pages
120
ISBN
9786139740789

Toxicidade e mecanismo de acao sobre leveduras e dermatofitos

Maysa Paula Da Costa Reis, Maria R R Silva, Carolina R Costa

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O aumento na resistencia aos antibioticos e os efeitos colaterais dos antifungicos disponiveis tem aumentado a necessidade de desenvolver novos e mais eficazes agentes antifungicos. Entre os compostos extraidos de plantas, os flavonoides sao considerados como possiveis fontes de novos agentes terapeuticos para infeccoes fungicas, bacterianas e virais. O mecanismo de acao antifungica e a toxicidade de fisetina, flavonoide com atividade antifungica previamente estabelecida para o complexo de especies Cryptococcus neoformans e dermatofitos, foram determinados. Os resultados apresentados mostram um perfil favoravel para conduzir ao estudo e desenvolvimento desta substancia no tratamento de criptococose e dermatofitose.

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