Resourcing of Natural Products for the Development of Anticancer Leads
Shakeel U Rehman, Masood Ur Rahman
Resourcing of Natural Products for the Development of Anticancer Leads
Shakeel U Rehman, Masood Ur Rahman
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The book describes the phytochemical investigations of three medicinal plants; Rhododendron lepidotum, Salvia sclarea and Podophyllum hexandrum, in addition to chemical modifications of D-pinitol, sclareol and podophyllotoxin, the major isolates from R. lepidotum, S. sclarea and P. hexandrum respectively, and bio-evaluation studies of the synthesized derivatives. The chemistry involved in the synthesis of analogs includes modern click chemistry, modified Heck Coupling reaction along with other conventional chemical reactions.
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