Geneticheskie Faktory Predraspolozhennosti K Raku Legkogo
Shutkin V a,Imyanitov E N,Brenishter S I
Geneticheskie Faktory Predraspolozhennosti K Raku Legkogo
Shutkin V a,Imyanitov E N,Brenishter S I
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Ochevidnoe sochetanie faktorov nasledstvennosti (gennyy polimorfizm) i faktorov okruzhayushchey sredy (tabachnyy dym) delaet rak legkogo interesnoy model'yu v izuchenii individual'noy onkologicheskoy predraspolozhennosti. Avtory vpervye obratili vnimanie na nasledstvennye aspekty izucheniya raka legkogo, ranee nasledstvennyy faktor voobshche nikto ne uchityval. Vpervye v rezul'tate nashikh issledovaniy vydvinuta i teoreticheski obosnovana kontseptsiya o dvukh osnovnykh patogeneticheskikh variantakh raka legkogo: nasledstvennogo i ekologicheskogo. Vse skazannoe podtverzhdaet neobkhodimost’ provedeniya kompleksnogo klinicheskogo, kliniko-genealogicheskogo i molekulyarno-geneticheskogo issledovaniy raka legkogo. Prichem, neobkhodimost’ podobnykh razrabotok opredelyaetsya eshche i tem, chto segodnya otsutstvuyut real'nye predposylki dlya provedeniya patogeneticheskogo lecheniya dannogo zabolevaniya. Vypolnennoe nami issledovanie v opredelennoy mere sposobstvuet vospolneniyu etogo probela. Kniga rasschitana na onkologov, genetikov, torakal'nykh khirurgov, semeynykh vrachey, pul'monologov, nauchnykh sotrudnikov, studentov meditsinskikh universitetov.
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