A group of young friends returning from a Key West vacation gone horribly wrong takes a wrong turn off a highway in the east Tennessee mountains, entering a dark realm that is both of the natural world and beyond it. A night of terror ensues, with some members of the group eventually arriving at an eerily imposing manor house. But the house is not a sanctuary from the horrors surrounding them. This is the HOUSE OF BLOOD. Here is where the Master of this dark realm resides, presiding over an empire of evil. The unsuspecting young travelers face a night of torture, degradation, and surrender to dark desires. Who among them, if any, will survive the night?