A comprehensive examination of the communication impairments that occur in association with multiple sclerosis. It covers the more widely recognized motor speech disorders seen in association with this condition, and the more recently identified language disorders reported to occur in persons with diseases of the cerebral white matter. A full description of the neuropathophysiology, epidemiology, aetiology, clinical manifestations and medical treatment of multiple sclerosis is also included. The findings of studies relating to the effects of multiple sclerosis on the physical functioning of the articulatory, velopharyngeal, laryngeal and respiratory systems are also included. In addition, contemporary methods for treating speech and language disorders in multiple sclerosis are described and discussed and recommendations are made.