Men's Health covers a wide range of issues, including diseases that affect only men, diseases typically considered to be "men's" diseases, and health-related issues important to men of specific ages. This first edition includes nearly 300 articles in two volumes on all aspects of health pertaining to men.

The content featured provides information on the anatomy and physiology of the male body; fathering children; diseases and conditions specific to men; psychological and sociological health; gay and transgender issues; health, exercise, and nutrition; issues pertaining to military servicemen, and the elderly; and more.

A wide variety of topics are included that are of interest to men at all stages of life. The goal of these volumes is to inform and educate men and others about men's health issues with reliable and useful sources of additional information.